Combo 5 tubes Klenzit MS Treatment of acne gel 15gr

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Klenzit MS topical cream 15g is an acne medication produced by Glenmark Pharmaceutical Company, imported directly from India, with the main ingredient adapalene in the form of a microporous drug delivery system, used to treat patients. have acne.

The product is prepared in a convenient 15g tube for topical application. During use, it is necessary to clearly distinguish between the two types of Klenzit MS and Klenzit C. Klenzit MS acne treatment cream only contains the active ingredient Adapalene in microsphere form to help control the active ingredient’s penetration into the skin, thereby reducing irritation. Not necessary on skin.

Ingredients:

Use:

Klenzit MS Treatment of acne gel 15gr is indicated in the following cases: Treatment of acne

Pharmacodynamic:

Adapalene is a retinoid derivative used to treat acne. Adapalene is 6[3-(1- adamantyl)-4-methoxyphenyl]-2-naphthoic acid. Adapalene regulates cell differentiation, keratinization and inflammation. All these processes play an important role in the pathogenesis of acne.

Adapalen has strong anti-inflammatory effects and is well tolerated when used topically, making it the drug of choice for treating acne.

The effect of adapalene, a retinoid derivative, on the epidermis is thought to be related to transcriptional control and gene repression mechanisms controlled by the binding of retinoids to retinoic acid receptors to initiate transcription. code, leading to proliferation and differentiation of keratinocytes.

Adapalene binds to retinoic acid-specific nuclear receptors but not to cytosolic protein receptors. Topical adapalene helps normalize hair follicle cell differentiation, leading to a reduction in the formation of small pimples.

Pharmacokinetics:

Absorb

Adapalene is poorly absorbed through the skin.

Allocation

Adapalene microparticles ranging in size from 3 – 10 µm penetrate the hair follicles and affect the sebaceous glands without distributing into the stratum corneum and causing irritation, thereby improving the effectiveness and safety of the drug.

Remove

Adapalene absorbed into the body is excreted mainly through bile.

How to use Klenzit MS and Dosage:

Using
Apply Klenzit MS acne cream once a day in the evening.
Apply a thin layer of medication (0.1% microparticle adapalen gel) to the damaged skin that has been washed and dried, avoiding the eye and lip areas.
Do not use the drug concurrently with other topical medications because it may cause irritation.

Dosage

Adult

• Microsphere adapalene gel is indicated for the topical treatment of comedones, papules and pustules in patients with mild to moderate acne.
• During the first weeks of applying the medicine, you can observe the phenomenon of acne spreading. This is due to the effect of the drug on previously invisible lesions and is not considered a reason to discontinue treatment.
• Treatment results are recorded after 8 – 12 weeks of taking the drug.

Children

• The safety and effectiveness of Adapalene use in children under 12 years of age have not been established.

Note:

The above dosage is for reference only. Specific dosage depends on physical condition and disease progression. For the appropriate dosage, you need to consult your doctor or healthcare professional.